Friday, April 19, 2013

New understanding of asthma development: Transmission of respiratory viruses in utero

Apr. 18, 2013 ? The most common cause of lower respiratory tract infections in infants and young children, respiratory syncytial virus (RSV), can be transferred during pregnancy to an unborn baby, according to Cleveland Clinic Children's Hospital research published online this week in the journal PLOS ONE.

In animal models, the study shows that RSV is able to spread across the placenta from the respiratory tract of the mother to the fetus, and is present in the lungs after birth, throughout development and into adulthood. RSV is considered the primary cause of infant pneumonia and has been implicated in the development of asthma.

"Epidemiologic evidence suggests that early-life RSV infection predisposes children to recurrent wheezing and asthma," said Giovanni Piedimonte, M.D., the study's lead author and Chairman of Cleveland Clinic Children's Hospital and the Pediatric Institute. "This study challenges the current paradigm that RSV infection is acquired only after birth and shifts attention to prenatal effects of the virus, which may result in more severe and lasting consequences by interfering with an unborn baby's critical developmental processes."

Research was completed in an animal model, in which rats were inoculated with RSV during midterm pregnancy. Of those infected, RSV was found in 30 percent of fetuses, as well as in the lungs of 40 percent of newborns and 25 percent of those that reached adulthood.

Dr. Piedimonte has been the principal investigator or co-investigator of more than 30 research projects, and has authored and co-authored more than 250 journal articles, book chapters, monographs, editorials and abstracts. He holds 17 international patents and is frequently invited to speak nationally and internationally.

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Story Source:

The above story is reprinted from materials provided by Cleveland Clinic, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Giovanni Piedimonte, Cheryl Walton, Lennie Samsell. Vertical Transmission of Respiratory Syncytial Virus Modulates Pre- and Postnatal Innervation and Reactivity of Rat Airways. PLoS ONE, 2013; 8 (4): e61309 DOI: 10.1371/journal.pone.0061309

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/CoZlrlRT8fk/130418214051.htm

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Purported photos suface of less expensive iPhone plastic backing

Photos of supposed rear casing to lower-cost iPhone surface

The less expensive iPhone has been rumored for a long time -- a way for Apple to cater to emerging markets and entry-level, off-contract customers -- but so far it's remained little more than a myth. Today, case manufacturer Tactus claims to have an image of the rear casing for just that device.

Aligning with previous rumors, the photo in question shows a white, plastic rear casing that looks like a fusion between an iPod classic and an iPhone 3G/iPhone 3GS rear housing. Tactus is also claiming that the low cost iPhone will come in 5 colors - black, white, red, yellow, and blue. As far as the display is concerned, Tactus is saying it will stick with a 3.5" retina display as opposed to rumors of a 4" display similar to the iPhone 5. Likewise, a 5mp camera and an A5 processor are included in their rumors.

While iMore hasn't heard anything along those lines, all of that makes sense to keep costs down and serve just exactly the type of market a lower-cost iPhone is meant to serve.

As far as whether or not this photo is legitimate, it's impossible to say at this point. Supply-chain sources leak, and it's possible case manufacturers have contacts at device manufacturers, or it's possible they just had the resources to mock up something based on what they heard, or based on extant rumors.

So file this under noise for now, but interesting noise. And in the meantime, would you buy a lower cost iPhone if it looked something like this?

Source: Tactus via MacRumors

    


Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/csdFyFyFSuc/story01.htm

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Thursday, April 18, 2013

Christopher Nolan's 'Interstellar' And 'Transformers 4' Will Be Shot In IMAX

Paramount Pictures has some big plans for its future with IMAX. The studio revealed at CinemaCon that it has signed a deal to shoot five of its upcoming films using IMAX cameras, and IMAX chairman Greg Foster announced two of them at CinemaCon's opening presentation. Honestly, the two pictures selected shouldn't come as much of [...]

Source: http://moviesblog.mtv.com/2013/04/16/christopher-nolan-interstellar-imax/

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Doctor who helped victims: People were 'laying in a pile'?

News

4 hours ago

Dr. Allan Panter felt the first blast as he waited at the finish line to cheer his wife as she completed her 16th Boston Marathon. He saw the people immediately next to him drop.

Incredibly, ?I was just standing there without a scratch,? the emergency room physician recalled Tuesday for TODAY?s Matt Lauer.

?I realized that all the people to what had been to my left had gone down, and just started helping with the other bystanders, pulling people, actually, apart because they were laying in a pile, basically with mangled limbs and started working on each person as you could,? he said.

Panter said one victim he helped was a man who lost both legs beneath the knees.

Story: Witness who ran toward marathon bomb 'saw bodies flying'

?He was pretty much as you would describe in shock,? he said. ?He was mumbling words but not coherently.?

Meanwhile, his wife, Theresa Panter, was frantically trying to make sure her husband of 30 years was safe. She was directed along with other runners to a safe area but it took more than an hour before she reached her husband.

Story: Boston marathon victims include two brothers who each lost a leg

?I was grabbing phones where they had held us and no calls. We couldn?t get any calls out,? she said. ?So I didn?t know. It was upsetting.?

Her husband praised the volunteers who immediately jumped in to help the victims.

"The sidewalk volunteers, instead of running away, they stopped and fell and worked the people,? he said.

Panter said he also was impressed with the team and supplies he encountered in the medical tent.

?It was all that an ER physician could ask for. There were cots, IVs, nurses and physicians,? he said. ?It was well prepared.?

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2ac91e18/l/0L0Stoday0N0Cnews0Cdoctor0Ewho0Ehelped0Evictims0Epeople0Ewere0Elaying0Epile0E1C9364931/story01.htm

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Monday, April 15, 2013

Wood Camera (for iPhone)


Wood Camera is regularly one of the most popular photo editing apps in the iTunes App Store, and it does offer more editing options than the wildly popular Instagram. Its interface is clear and usable, and you can see effect filters while you're taking pictures. But Wood lacks its own photo-specific social network (let alone any web view at all), which you get not only with Instagram but also with EyeEm, BeFunky, and Flickr.? Nor do you get any shooting helpers like those in Camera+. Let's take a deeper look at what you do get for your hard-earned ninety-nine cents.

Install
Wood Camera is optimized for iPhone 5, but runs on any device running iOS 5 and up. The app took up 37.6MB of my phone's storage, 2MB more than Instagram but 3MB less than BeFunky. When your iPhone is getting loaded up with photos and music, as mine is, these things matter. When you first run the app, it asks to send you push notifications, something more and more apps are doing, meaning there's a good chance you'll be endlessly interrupted if every app you install wants to notify you constantly. I'm not really sure I need notifications from a photo editing app, but I pressed OK anyway, for testing purposes. I also got the message asking me to rate Wood Camera?before I'd even started using it!?

Interface
Once installed and messages OKed, Wood Camera's interface is simple, clear, and well designed. The first screen shows you how to use it with overlaid instructions and arrows:? Single-tap for preview, double-tap for editing?simple enough. There's also a Camera button at bottom center?standard in iPhone photo apps. Only two options flank this: Camera Roll and Photo Paste. Just three controls live at the top of the screen, too?a settings gear, thumbnail/full view slider, and share button. It's a completely clear, intuitive layout.

Shooting with Wood Camera
Shooting in the built-in camera interface is different from using the default iPhone camera app and from the current Instagram app. You can see retro effect filters as you shoot, and you can shoot in rapid succession. Instagram used to let you see the filters as you shot, but removed that capability; if you like this, Wood is a good fit.

One quibble with shooting in the Wood app is that there's no visual clue that you've taken a shot, like the default iPhone camera's animation of the photo flying down to the Camera roll icon. You just hear the shutter click, but if you're in a noisy environment, you get no feedback. The Wood filters are all named for world cities, which doesn't give you much of an idea of what they do. I prefer the straightforward effect names used in BeFunky, such as "Warming," "Cooling," and "LomoArt." Once you've shot a few pictures, hit Done, and the app starts "importing them."

Editing and Enhancing Your iPhone Photos
So as you've seen, an effect can be applied the moment you shoot your photo. So what else can be done afterwards? A lot! After selecting an image from the thumbnail grid of those you shot, hitting Edit lets you, rotate and straighten, crop, change the effect filter (here called a "lens"), texture, tiltshift/vignette, and frames. Here, you can adjust the intensity of the effect filters, something not available in Instagram. Several of these tools aren't available in Instagram, but in Wood I still miss any basic photo corrections like brightness, contrast, and white balance. Aviary and BeFunky give you all this and more.

A nice selection of frames is available, film, print, and rounded borders among them, both dark and light. Unlike in Instagram, which ties borders and frames to each filter, you can use any frame border with any filter effect in Wood Camera. Another interesting choice not found in most iPhone photo apps is Textures. This lets you apply film-grain, wrinkly paper,

At first, I was concerned that once I tapped Done after making an edit, the photo was forever changed, but opening it back up in the tool you used and clicking the None icon, the first one, let me undo. You can also choose a main setting to save any pictures you take in the app to your Camera Roll by default. A standard Undo arrow would be helpful, though.

I have to say that, though Wood had more filters than Instagram, I didn't love the selections; most simply bumped up the warm or cool colors, some made it monochromatic and maybe added vignetting. Both Instagram and BeFunky offer more striking options. The tilt-screen effect is inferior to Instagram's, which lets you choose a linear as well as circular focus area and resize them. Wood only offers a circle of focus you can move around but not resize. The preview thumbnails for filters use a stock photo, rather than your shot image, so you can't see what it looks like with your image till after applying.?

Sharing
Wood doesn't include its own photo social network?or even any web view for photos use edit in it?like that offered by Instagram, EyeEm, and BeFunky, but it does include more than the standard external sharing options. Along with the expected Facebook, Twitter, Flickr, and even Instagram output options, you can save to your Dropbox (if you have its app installed) or to other apps that can accept photos, such as SkyDrive. In another example of lack of feedback, when I tried posting to Facebook, the app didn't notify me whether the post was successful or not. (Since my Wi-Fi and 3G connections were spotty, it wasn't a given that the photo made it to my page.)?

Good Wood?
Wood Camera is a perfectly pleasant iPhone photo app, with a clear, usable interface and more photo manipulation options than some of its peers, including Instagram. But if you're going to build a photo app with more photo editing than the competition, you really have to include adjustment for brightness, contrast, and color settings. You get these with our Editors' Choice iOS photo editors, Snapseed and Adobe Photoshop Touch, as well as in Aviary, Camera Genius, Camera+, and BeFunky.

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/KpcmEycvyU0/0,2817,2417710,00.asp

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